Hypertensive urgency: an important aetiology of rebound hypertension

Valproate Induced Hypertensive Urgency

Valproate is a medication used in the treatment of seizures, bipolar disorder, migraines, and behavioral problems. Here we present a case of an 8-year-old boy who presented with hypertensive urgency after initiation of valproate. Primary treatment of his hypertension was ineffective. Blood pressure stabilization was achieved following discontinuation of valproate. Clinicians should be aware of ...

Early adiposity rebound is an important predictor of later obesity.

Obesity Task Force cutoffs. In average, obesity started at the age of 5 years, while AR started 3 years earlier (figure 1). The very early AR recorded in obese subjects suggests that determinants of future risks have operated early in life. In conclusion, BMI growth trajectories of obese individuals do not generally follow an elevated percentile throughout childhood but rather indicate normal o...

St George Hospital, Renal Department – INTERNAL ONLY Treatment of Chronic Hypertension and Hypertensive Urgency on Haemodialysis

Acute control of blood pressure on haemodialysis (HD) should be differentiated from chronic BP control; Hypertension in HD is multi-factorial; Patients requiring total ultrafiltration volume greater than 2.5 kg may have an elevation in pre-systolic and pre-diastolic BPs; Larger fluid removals of range >10-13ml/hour/kg are associated with increased all cause and cardiovascular mortality; Both pr...

Is vasopressin an important hypertensive hormone?

To generate quantitative data relating to the potential hypertensive activity of arginine vasopressin (AVP), 140 and 560 microunits AVP/kg/min were infused chronically in both normotensive dogs and dogs made hypertensive by chronic infusion of either angiotensin II (AII) or aldosterone. The lower rate of AVP infusion increased plasma AVP concentration from 0.4 +/- 0.1 microunits/ml. Mean arteri...

The aetiology of systemic hypertension.